There are two different questions being discussed in this thread, albeit related:
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is there still merit in separating out the amplification into two boxes, pre and power?
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Does a preamp make a positive difference where a source is capable of driving a power amp withou using a pre? [but unspoken: preamp = as currently implemented, with power amps as currently implemented]
Regarding the first question, I don’t think anyone has either countered or bettered my argument earlier in this thread (post 8, on the first day), namely that it depends on whether sources include low level signals, the challenge with low level signals being the original reason for separating out into pre- and power-. In that post I included a suggestion for what would be a better approach given that many sources these days are high level, unlike when the splitting originally became recognised as desirable.
As for the second question, it almost certainly will depend at least in part on the source and the power amp in question (their characteristics and how they interact), and on whether the preamp under consideration adds a sound signature that the listener likes. And of course that can only be determined for certain by hearing: hearing the specific source and power amp, with and without a preamp, and likely differing with different preamps.
For myself I compared Hugo into Bryston power amp direct compared to through a Tag MacLaren preamp, and found no obvious difference (I didn’t do extensive comparisons) so I simply went for the direct route, and when replaced Hugo with Dave nothing made me feel any need to try a preamp, it sounding so good. One day I might be tempted to hear Naim power amps in my system, and if I do then that would be an obvious time to try a Naim pre - but at present with no Naim dealer in reach it won’t happen, and a NAC is an awful lot of money for a buffer/modifier!