Thanks for the interest - I have spent more time investigating.
More concerning than the disk swapping question is -
I read a couple of items online reporting issues with the QNAP NS-251+, re: the fan & a .tmp file causing a problem
I asked on QNAP forum and got the reply below today (with the link removed) :
" At the time of introduction the bug in the Intel processor range causing this problem was not known and it is affecting more products using one of the affected processors, not only some QNAP NAS’s in the x51/x53 range. What is annoying to say the least is that QNAP plays dumb about the issue although it’s a well known problem as you have found out. The 451+ is internal basically the same NAS as the 251+, just 4 bays instead of 2. With same processor and bug. Buying that one at the time would not have prevented you from this situation. And yes, with another 251+ you can just swap the drives, just make sure to use the drive in the same drive bay. In fact, you can do this with many other QNAP’s The current 251D looks like the direct replacement for your 251+ and has a newer Intel processor without that bug. "
So it looks like I will be buying a different model, I have someone to speak to on Wednesday who should provide a definitive answer - Not good !?