I used Neat MFS for many years, a speaker I believe still punches well above its weight. A superb match for the 300 and only changed because the system ended up in a much bigger room, 6m x 11.4m.
Now using Magico S3mk2. These are in another league to the Neats but although the 300 drives them well, I know they have much more to give so I plan to swap the 300 for a 500 in the next couple of years.
Firing down the length of the room, both speakers ended up in similar positions, around 2.38m from the front wall and 1.68 from side walls. 2.65 apart and I sit 2.75 away. All measured to the centre line of the front baffle.
In both cases, a little toe in but not aimed at the listener, the Mágicos more toed in than the Neats.
My ceiling is irregular, lowest in the corners behind the speakers (1.3m) and highest in the middle of the room (3m). Flat concrete construction with an open, descending stairway. The irregularity is beneficial, as is the size of the room but RT is greater than I would like and am working with GIK on treatment options. The need to treat seems more obvious with the Mágicos than it did with the Neats. That said, we will be reducing the 11.4m length to around 7.6m soon (adding a bedroom/office) so that may completely change the character of the room…